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Croda
Design and development of lipid modified arginine based self-nanoemulsifying drug delivery systems…
Cefixime (CEF) has numerous potential applications in the treatment of bacterial infections. However, due to its decreased cellular internalization, poor aqueous solubility, rapid intestinal hepatic metabolism, its clinical efficacy is limited. The purpose of this research was to develop an…
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Xanthan and gum acacia modified olive oil based nanoemulsion as a controlled delivery vehicle for…
In this study, olive oil nanoemulsion modified with xanthan gum and gum acacia was explored as a potential controlled topical delivery vehicle. Oil-in-water nanoemulsion formulated with optimized composition of olive oil, tween 80, and water was used as the drug carrier and further modified with…
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Preparation, Characterization and Stability Study of Eugenol-Loaded Eudragit RS100 Nanocapsules for…
Eugenol is a phenolic compound with numerous biological activities. It is widely used in dentistry to treat toothache and pulpitis. In particular, eugenol may be used for tooth whitening procedures to minimize dental sensitivity in patients. However, eugenol has some disadvantages such as its…
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Chitosan/Solid-Lipid Nanoparticles Hybrid Gels for Vaginal Delivery of Estradiol for Management of…
Hormonal replacement therapy is the mainstay treatment to improve quality of life and reduce mortality. With the increasing number of young women with early menopause, women now live longer (increased life expectancy). However, poor patient compliance with oral estrogen therapy has emerged.…
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Formulation of Silymarin-β Cyclodextrin-TPGS Inclusion Complex: Physicochemical Characterization,…
Abstract
Silymarin (SIL) is a poorly water-soluble flavonoid reported for different pharmacological properties. Its therapeutic applications are limited due to poor water solubility. In this study, the solubility of silymarin has been enhanced by preparing freeze-dried binary and ternary complexes…
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Donepezil and Embelin loaded Nanostructured lipid carriers for direct brain delivery as an…
Donepezil hydrochloride (DPL) and Embelin (EMB) loaded Nanostructured Lipid Carriers (NLCs) have been developed and optimized to achieve optimal drug loading, safer nasal delivery, effective neuronal/cell uptake, enhanced brain accessibility, controlled release, and desired therapeutic effect.…
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Formulation and in vitro skin diffusion of colchicine using different drug delivery vehicles
Introduction
Historically known as “the disease of kings,” gout is one of the oldest known types of arthritis, affecting more than 40 million people worldwide, prevalent in patients between 30 and 50 years of age, and frequently experienced more by males than females , , , ]. It is a result of…
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Development of Simvastatin-Loaded Particles Using Spray Drying Method for Ex Tempore Preparation of…
In this work, a spray drying method was developed to produce drug/polymer (simvastatin/polycaprolactone) microparticles that have the potential to be used as a pre-formulation for ex tempore preparation of 2D printing cartridges. An experimental model was designed with the process parameters set to…
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Co-delivery of exemestane and thymoquinone via nanostructured lipid carriers for efficient breast…
Owing to the poor therapeutic outcomes with a single chemotherapeutic agent, the co-delivery of agents for achieving high efficacy in managing breast cancer has been gaining a lot of interest lately. The objective of the present study was the fabrication and optimization of nanostructured lipid…
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Formulation Design and characterization of Antifungal Emulgel for Topical Delivery
Emulgel is the latest generation in novel drug transport device used for manage launch of emulsion and gel for the reason of topical use. The steadiness of emulsion is increased, while it is integrated into gel. Miconazole is an antifungal drug has been used inside the remedy of dermatophytic…
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