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Croda
Virodex™: exploring our innovative solution to the Triton™ X-100 ban
Triton™ X-100 is a widely used non-ionic surfactant and emulsifier, with a range of applications including viral inactivation, cell lysis and protein solubilisation. Triton™ X-100 belongs to the substance group Phenol ethoxylates which are considered to be hazardous to the aquatic environment and a…
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Protein corona formation on lipidic nanocapsules: Influence of the interfacial PEG repartition
The parameters currently used for characterization of nanoparticles, such as size and zeta potential, were not able to reflect the performance of a nanocarrier in the biological environment. Therefore, more thorough in vitro characterization is required to predict their behavior in vivo, where…
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Rosacea Topical Treatment and Care: From Traditional to New Drug Delivery Systems
Rosacea is a multifactorial chronic inflammatory dermatosis characterized by flushing, nontransient erythema, papules and pustules, telangiectasia, and phymatous alterations accompanied by itching, burning, or stinging, the pathophysiology of which is not yet fully understood. Conventional topical…
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Virodex™ – For viral inactivation and cell lysis applications for bioprocessing
Are you utilising viral inactivation and cell lysis techniques in your bioprocessing applications?We’re introducing our new range of detergents specifically designed to support the key steps in your biomanufacturing processes.
The Virodex™ range for viral inactivation and cell lysis…
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Lipid-Based Delivery Systems for Flavonoids and Flavonolignans: Liposomes, Nanoemulsions, and Solid…
Herbal chemicals with a long history in medicine have attracted a lot of attention. Flavonolignans and flavonoids are considered as two classes of the above-mentioned compounds with different functional groups which exhibit several therapeutic capabilities such as antimicrobial, anti-inflammatory,…
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Highly Concentrated Emulsions Containing High Loads of Pterostilbene
Abstract
Pterostilbene is a highly researched molecule due to its bioactivity. However, its hydrophobicity limits its application. For this reason, researchers have sought to encapsulate pterostilbene (namely, in oil-in-water emulsion) to increase its availability. Studies are lacking when it comes…
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Nanocellulose-Based Film-Forming Hydrogels for Improved Outcomes in Atopic Skin
Atopic dermatitis (AD) is a chronic inflammatory skin disease characterized by impaired skin barrier function. Amongst the various dermal formulations that are being used and/or investigated for AD treatment, one of the advanced approaches is the use of hydrogels as film-forming systems that are…
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A study of microemulsion systems for transdermal delivery of risperidone using penetration enhancers
Abstract
The aim of this study was to develop and characterize microemulsion formulations using penetration enhancers as potential transdermal delivery systems for risperidone. Initially, a simple formulation of risperidone in Propylene Glycol (PG) was prepared as a control formulation, together…
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Beta Caryophyllene-Loaded Nanostructured Lipid Carriers for Topical Management of Skin Disorders:…
This work aimed to overcome the disadvantages of the oral administration of beta-caryophyllene and boost efficiency by developing a nanostructured lipid carrier for topical administration of the drug in skin disorders. The heat emulsification method was utilized to produce beta-caryophyllene-loaded…
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Dual drug loaded nanostructured lipid carrier for cytotoxic effect against breast cancer-a drug…
Abstract
In the present study nanostructured lipid carrier with a combination of Metformin (MET) and Thymoquinone (THY) was developed, characterized, and was further evaluated for cytotoxic effect on breast cancer cells. The optimized MET-THY-NLCs were found with the size 78.99 nm with entrapment…
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