Croda

Numerous problems affect oral health, and intensive research is focused on essential oil–based nanoemulsions that might treat prevent or these problems. Nanoemulsions are delivery systems that enhance the distribution and solubility of lipid medications to targeted locations. Turmeric (Tur)- and…
Read More...

The human eye is a sophisticated organ with distinctive anatomy and physiology that hinders the passage of drugs into targeted ophthalmic sites. Effective topical administration is an interest of scientists for many decades. Their difficult mission is to prolong drug residence time and guarantee an…
Read More...

A mucoadhesive microemulsion of lipophilic silymarin (SLMMME) was developed to treat Parkinson’s disease (PD). Optimization of the SLM microemulsion (ME) was performed using Central Composite Design (CCD). The composition of oil, surfactant, co-surfactant, and water was varied, as per the design, to…
Read More...

The goal of this study was to see if microemulsions might be used as a transdermal drug delivery system for acemetacin (ACM). Microemulsions containing isopropyl myristate, Tween 80, Transcutol HP, Labrafil M1944 CS, ethanol, and distilled water were used to create pseudo-ternary phase diagrams. In…
Read More...

Bioavailability of weakly basic drugs may be disrupted by dramatic pH changes or unexpected pH alterations in the gastrointestinal tract. Conventional organic acids or enteric coating polymers cannot address this problem adequately because they leach out or dissolve prematurely, especially during…
Read More...

Curcumin (CUR) has been shown to possess significant anti-inflammatory properties and significant wound healing potential. Additionally, lignin (LIG) is a renewable biomacromolecule with well-known antioxidant and antimicrobial properties, which makes this biomacromolecule a good candidate to be…
Read More...

The aim of the current study was to develop an ocular Self-nanoemulsifying drug delivery system (SNEDDS) loaded with Brimonidine tartrate (BRT) and evaluate its ex-vivo permeability. SNEDDS loaded with BRT were prepared by low energy method. Physicochemical properties, drug release, ex-vivo…
Read More...

Discover the Benefits of Super Refined Excipients Excipient choice can make all the difference in successful formulation development. The selection of pharmaceutical excipients in a drug formulation can have a significant impact on development timescales, Active Pharmaceutical Ingredient (API)…
Read More...

Gene-editing technology is moving from the research lab to the clinic — one of the most eagerly anticipated biopharma developments in recent history. One of the biggest hurdles to the development of successful gene-editing therapeutics is effective delivery of the large and sensitive components…
Read More...

The goal of current research was to develop a new form of effective drug, curcumin-loaded solid lipid nanoparticles (Cur-SLNs) and test its efficacy in the treatment of lung cancer. Different batches of SLNs were prepared by the emulsification–ultrasonication method. For the optimization of…
Read More...