Croda

Cancer refers to a collection of diseases that have abnormal cell growth as their hallmark. This inability of cytotoxic agents to distinguish between rapidly dividing healthy cells andrapidly multiplying cancerous cells produces the most notorious adverse effects of cytotoxicanticancer agents. As an…
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The acidic pH of healthy skin changes during wound healing due to the exposure of the inner dermal and subcutaneous tissue and due to the potential colonization of pathogenic bacteria. In chronic non-healing wounds, the pH values vary in a wide pH range but the appearance of an alkaline shift is…
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This work aimed to optimize a celecoxib (CXB)-loaded solid lipid nanoparticles (SLN) colon delivery system for the enhancement of anticancer activity. An ultrasonic melt-emulsification method was employed in this work for the preparation of SLN. The physical attributes were characterized for their…
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While the intranasal administration of drugs to the brain has been gaining both research attention and regulatory success over the past several years, key fundamental and translational challenges remain to fully leveraging the promise of this drug delivery pathway for improving the treatment of…
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The manufacturing of stable emulsion is a very important challenge for the cosmetic industry, which has motivated intense research activity for replacing conventional molecular stabilizers with colloidal particles. These allow minimizing the hazards and risks associated with the use of conventional…
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Rheumatoid arthritis is a chronic autoimmune disease, with the features of recurrent chronic inflammation of synovial tissue, destruction of cartilage, and bone erosion, which further affects joints tissue, organs, and systems, and eventually leads to irreversible joint deformities and body…
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A Croda Pharma Webinar - July 13, 2022 Patient compliance is paramount to the success of topical drug products, and appealing aesthetics are all-important in achieving that compliance. Without an understanding how to employ a variety of emulsifier systems, chances of success can be low. Join…
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Croda International Plc (‘Croda’ or ‘the company’), the company that uses smart science to create high performance ingredients and technologies that improve lives, announces that it has entered into a cooperative agreement with the United States (‘U.S.’) government in which the government will…
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The current research attempts different approaches to overcome the poor dissolution of budesonide (a poorly water-soluble drug) from pellet formulations. Various methods such as liqui-pellet (LP) and pellets made of solid dispersion (SDP) were employed and compared to conventional pellets (CP). In…
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Many formulation strategies have been employed to improve ocular bioavailability of topical eye drops. The aim of this study was to develop and evaluate a series of solid lipid nanoparticles coated with poly(2-ethyl-2-oxazoline) and chitosan for ocular delivery of ciprofloxacin. Ciprofloxacin-loaded…
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