DFE Pharma

The whitepaper shows results of tested 20 lactose grades in 3D powder bed printing. The primary objective of this study was to select lactose with sufficient flow, wetting and binding to be used effectively in the powder bed 3D printing of pharmaceuticals. Please check your email after…
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Working with the Netherlands Organization for Applied Scientific Research (TNO), DFE Pharma tested 20 lactose grades in 3D powder bed printing. The primary objective of this study was to select lactose with sufficient flow, wetting and binding to be used effectively in the powder bed 3D printing of…
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The aim of this study was to develop direct compressed and lyophilized fast disintegrating/dissolving tablets (FDTs) that enhanced disintegration and dissolution of deferasirox, a drug with poor solubility and bioavailability. Although there are conventional oral tablets and tablets for oral…
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This chapter describes the application of lactose as excipient in the pharmaceutical industry. About 60%–70% of pharmaceutical dosage forms contain lactose, and in volume it is one of the biggest pharmaceutical excipients. Lactose can have several functions in a dosage form: as a filler to…
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The overall objective of this work is to understand how excipient characteristics influence the drug product quality attributes and process performance of a continuous twin screw wet granulation process. The knowledge gained in this study is intended to be used for Quality by Design (QbD)-based…
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