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Gangwal
Formulation development, in-vitro and ex-vivo evaluation of dry adsorbed solid lipid nanoparticles:…
Abstract
Aim: The present study was aimed at preparing stable dry adsorbed nanoparticles (DANs) of olanzapine (OLZ) loaded solid lipid nanoparticles (SLNs) for sustained release.
Materials/methods: OLZ SLNs were prepared by hot melt emulsification and ultrasonication using Precirol ATO 5 (PRE)…
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Design, development and scale up studies of metformin hydrochloride multiparticulate system: A…
Metformin hydrochloride (MH) is prescribed for treating diabetes mellitus. The most popular dosage form, viz., tablets has a bulky nature as MH dose ranges up to 1000 mg leading to large size. In geriatric or dysphagic patients, due to altered physiology, swallowing such bulky formulation is…
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Advanced process automation of a pharmaceutical continuous wet granulation line: Perspectives on the…
Abstract
Pharmaceutical continuous manufacturing provides the appropriate tools (e.g. the understanding of process dynamics and appropriate and adaptable control strategy) in order to deal with Quality-by-Design expectations and even to the future smart manufacturing described by…
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