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IFF
Comprehensive Analysis of Novel Synergistic Antioxidant Formulations: Insights into…
Abstract
(1) Background: Oxidative stress plays a pivotal role in the pathogenesis of various diseases, including neurodegenerative disorders, cardiovascular diseases, cancer, and diabetes, highlighting the pressing need for effective antioxidant interventions.
(2) Methods: In this study, we aimed…
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Mannitol-coated hydroxypropyl methylcellulose as an alternative directly compressible controlled…
One of the most common forms of controlled release technology for oral drug delivery comprises an active ingredient dispersed in a hydrophilic matrix forming polymer such as hydroxypropyl methylcellulose (HPMC), which is tableted via direct compression. However, HPMC may pose problems in direct…
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Long-acting transdermal drug delivery formulations: Current developments and innovative…
Transdermal administration remains an active research and development area as an alternative route for long-acting drug delivery. It avoids major drawbacks of conventional oral (gastrointestinal side effects, low drug bioavailability, and need for multiple dosing) or parenteral routes (invasiveness,…
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Evaluation of binders in twin-screw wet granulation – Optimization of tabletability
Abstract
The influence of hydroxypropyl cellulose type (HPC-SSL SFP, HPC-SSL), concentration (2 %, 3.5 %, 5 %) and filler (lactose, calcium hydrogen phosphate (DCP)/microcrystalline cellulose (MCC)) on twin-screw wet granulation and subsequent tableting was studied. The aim was to identify the…
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Methocel™ Cellulose Ethers – A product that can do it all
THE POSSIBILITIES ARE ENDLESS
Pharmaceutical companies are continuously looking for ways to innovate – through new technologies such as controlled release systems and oral films, or through faster and more efficient manufacturing processes. Did you know that just one product can help do all of…
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Hollow microneedles for ocular drug delivery
Microneedles (MNs) are micron-sized needles, typically <2 mm in length, arranged either as an array or as single needle. These MNs offer a minimally invasive approach to ocular drug delivery due to their micron size (reducing tissue damage compared to that of hypodermic needles) and overcoming…
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Amorphous solid dispersion of a binary formulation with felodipine and HPMC for 3D printed floating…
Abstract
This study focuses on the combination of three-dimensional printing (3DP) and amorphous solid dispersion (ASD) technologies for the manufacturing of gastroretentive floating tablets. Employing hot melt extrusion (HME) and fused deposition modeling (FDM), the study investigates the…
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The effect of glidant on the tabletting behavior of common pharmaceutical excipients
Abstract
Glidant used for the purpose of powder flowability enhancement is well known within the pharmaceutical industry to improve tablet manufacturing. Despite the widespread use of glidant for this purpose, the effect of glidant on the effect of tableting behavior is not well studied. To address…
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Take Control of Your Formulations – An essential guide for selecting METHOCEL™ hydroxypropyl…
SYNOPSIS
Controlled release (CR) formulations are revolutionizing drug delivery across the pharmaceutical landscape. Offering advantages like enhanced therapeutic outcomes and patient convenience, this innovative drug formulation is experiencing rapid global growth. The popularity of CR…
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Controlled Release: Timing is Everything
IFF officially release a new Controlled release platform on 15th of May 2024. Here you get a deeper insight in the "Timing is Everything" platform where you can learn about pharmaceutical formulations to benefit patients and the importance of controlled release of active ingredients.
No…
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