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JRS Pharma
JRS PHARMA Announces New Clean Label Excipient LUBRITAB® RBW
Patterson, NY USA, November 2022 - JRS PHARMA proudly introduces its newest all-natural excipient: LUBRITAB® RBW. Developed as a lubricant for tablet and capsule formulations, LUBRITAB® RBW is suitable for use in direct compression and continuous manufacturing, as well as in wet or dry granulation…
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Compression Density as an Alternative to Identify an Optimal Moisture Content for High Shear Wet…
Pellet production is a multi-step manufacturing process comprising granulation, extrusion and spheronisation. The first step represents a critical control point, since the quality of the granule mass highly influences subsequent process steps and, consequently, the quality of final pellets. The most…
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How to Improve Solubility and Dissolution of Irbesartan by Fabricating Ternary Solid Dispersions:…
The purpose of this study is to improve the solubility and dissolution of a poorly soluble drug, Irbesartan, using solid dispersion techniques. For that purpose, different polymers such as Soluplus®, Kollidon®VA 64, Kolliphor®P 407, and Polyinylpyrrolidone (PVP-K30) were used as carriers at…
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Effect of a superdisintegrant on disintegration of orally disintegrating tablets determined by…
Abstract
The disintegration time is critical for characterizing orally disintegrating tablets (ODTs), according to regulatory standards. The current study aimed to assess the effect of superdisintegrants such as sodium starch glycolate, croscarmellose sodium, and crospovidone on the…
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Recent advancements in additive manufacturing techniques employed in the pharmaceutical industry: A…
Abstract
The 3–dimensional printing process (3DP) was patented in the 1980s, but the utilization of this process has expanded substantially over the past decade, to which the pharmaceutical industry is a major contributor. With increasing interest, researchers across the globe are striving for the…
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Direct Compression of Probiotic Tablets with PROSOLV® EASYtab Nutra
Abstract
Although probiotics are mostly administered in the form of capsules, there are some advantages of tablets in terms of production effort, cost efficiency and stability of the probiotic bacteria. As probiotics are sensitive to high pressure and temperature, it is essential to select…
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A compactibility-based lubricant dispersion model describing the effect of formulation and paddle…
In rotary tablet presses, the powder flow into the dies is typically facilitated by paddle feeder. For internally lubricated formulations, the shear forces exerted by the paddle rotation can result in a considerable decrease in tablet strength due to the dispersion of lubricant agglomerates.…
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Effect of binder type on physical and in vitro properties of high dose inosine acedoben dimepranol…
The present work was conducted with the aim to formulate and evaluate the immediate release of 1000 mg tablets containing Inosine Acedoben Dimepranol (IAD). All the samples of the tablets containing 1000 mg IAD were prepared by conventional wet granulation method. Various type of binders like…
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Influences of different microcrystalline cellulose (MCC) grades on tablet quality and compression…
Microcrystalline cellulose (MCC) is one of the most commonly used excipients in tablet formulations. At present, numerous grades of MCC are available for pharmaceutical manufacturing and significantly differ in particulate and powder properties. The choice of MCC is important to the development of a…
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Your visit at CPHI worldwide 2022 in Frankfurt
CPHI worldwide opens its doors again. This year in Frankfurt at the Messe Frankfurt. In two weeks, from 1st to 3rd November, you can finally have a face-to-face chat with visitors and exhibitors again. As usual, InnoPack, P-MEC, FDF, ICSE and BioProduction will be held together with CPHI.
The…
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