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JRS Pharma
Prolongation of the gastric residence time of caffeine after administration in fed state: Comparison…
Abstract
The aim of the present study was to investigate the gastroretentive capacity of different formulation principles. This was indirectly determined by the absorption behavior of caffeine from the dosage forms. A slow and continuous appearance of caffeine in the saliva of healthy volunteers…
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Nano-encapsulation of probiotics: Need and critical considerations to design new non-dairy probiotic…
People worldwide need to improve their health or intention to control diseases more naturally through ingredients incorporated into foods and beverages, called functional foods. Functional foods include probiotic organisms and bioactive compounds incorporated into dairy and fermentable foods, whose…
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In Situ Gelling Nasal Drug Delivery System
Abstract
In the nasal cavity, nasal mucosa had a high blood perfusion rate, due to this the absorption of the drug is high as compared to other routes, as well as has increased good bioavailability of drugs at the systemic circulation. To improve the nasal retention time of in-situ gel with nasal…
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A comprehensive assessment of machine learning algorithms for enhanced characterization and…
Orodispersible films (ODFs) have emerged as innovative pharmaceutical dosage forms, offering patient-specific treatment through adjustable dosing and the combination of diverse active ingredients. This expanding field generates vast datasets, requiring advanced analytical techniques for deeper…
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A vascularized in vivo melanoma model suitable for metastasis research of different tumor stages…
Abstract
Although 2D cancer models have been the standard for drug development, they don't resemble in vivo properties adequately. 3D models can potentially overcome this. Bioprinting is a promising technique for more refined models to investigate central processes in tumor development such as…
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Elucidation of processing parameters for the reverse engineering of tablets
Abstract
Reverse engineering can assist in decoding the formula and manufacturing parameters employed in innovator formulations. Generic pharmaceutical industries use it to develop generic cheaper versions of innovator tablets. Herein, we report the systematic application of reverse engineering in…
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Vitafoods Geneva 2024 – with a focus on excipients
This year Vitafoods Europe opens its doors for the last time in Geneva at Palexpo.
From 14th to 16th May you can have a face-to-face chat with visitors and exhibitors again.
Pharma Excipients gives you an overview of the excipient suppliers, their booths, main topics and products in the…
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Polymeric Amorphous Solid Dispersions of Dasatinib: Formulation and Ecotoxicological Assessment
Abstract
Dasatinib (DAS), a potent anticancer drug, has been subjected to formulation enhancements due to challenges such as significant first-pass metabolism, poor absorption, and limited oral bioavailability. To improve its release profile, DAS was embedded in a matrix of the hydrophilic polymer…
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Topical pickering emulsion versus classical excipients: A study of the residual film on the human…
Abstract
The interest in Pickering emulsions is based on the possibility of replacing classical emulsifiers with solid particles. These emulsions are very attractive in the pharmaceutical field for their stability virtues and as a vehicle to deliver active ingredients. The study aimed to analyze…
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Development and application of control concepts for twin-screw wet granulation in the ConsiGma-25:…
Abstract
Traditional operation modes, such as running the production processes at constant process settings or within a narrow design space, do not fully exploit the advantages of continuous pharmaceutical manufacturing. Integrating Quality by Control (QbC) algorithms as a standard component of…
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