JRS Pharma

The aim of this work was to develop anti-stress compressed lozenges containing 100 mg of glycine and 250 mg of magnesium citrate obtained by the direct compression method. To choose optimal excipient composition providing the sufficient pharmaco-technical properties of the tablet blend, mechanical…
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Aim of this work is to apply protective and homogeneous shellac coating layers on the surface of hydrophilic open-pore cellulose aerogel particles with low densities ≤ 0.1 g/cm3 and high specific surface areas in the range of ~ 400–450 m2/g while keeping the aerogels’ microstructure intact during…
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Cannabidiol (CBD) is an alkaloid that can be found in the Cannabis species, currently used in United States of America under the name of Epidiolex®, which was approved by Food and Drug Administration (FDA) for seizures treatment. The purpose of this study was to investigate the structural…
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JRS cellulose products come in various shapes and structures. For their customers, it is not only essential, to receive excellent functionality in their applications, but also to understand how they can incorporate the fibers in their production lines. In large scale processes, parameters like…
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Introduction Lubricants play a critical role in the development process of tableting and capsule filling. For decades, magnesium stearate has been the most commonly used lubricant in pharmaceutical and nutraceutical tablet formulations, offering both functionality and cost-efficiency. As a…
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The current study evaluated the effect of location and amount of various superdisintegrants on the properties of tablets made by twin-screw melt granulation (TSMG). Sodium-croscarmellose (CCS), crospovidone (CPV), and sodium starch glycolate (SSG) were used in various proportions intra- and…
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This work explored 3D bioplotting to mimic the intrinsic hierarchical structure of natural articular cartilage. Alginate dialdehyde-gelatine (ADA-GEL) was used as a hydrogel ink to create hierarchically ordered scaffolds. In comparison to previously reported ADA-GEL compositions, we introduce a…
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Electrospinning is a technology for manufacture of nano- and micro-sized fibers, which can enhance the dissolution properties of poorly water-soluble drugs. Tableting of electrospun fibers have been demonstrated in several studies, however, continuous manufacturing of tablets have not been realized…
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Counterfeiting of the products for healing is as old as trading, and it is difficult to quantify the magnitude of the problem. It is known that substandard and/or falsified (SF) medicines are a growing global threat to health, and they cause serious social and economic damage. The EU has a strong…
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Novel calcium phosphate-based starter pellets were used to develop a biphasic-release multiple-unit pellet system (MUPS) with diclofenac sodium as a model drug in the form of hard gelatin capsules. For comparative purposes, corresponding formulations based on the inert cores made of microcrystalline…
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