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JRS Pharma
Obtainment of the spray-dried extracts of Peperomia pellucida L. (H.B.K.) using different…
Spray-dried extracts are prepared as powders or granules after solvent removal, which can be obtained in the presence or absence of pharmaceutical adjuvants. This work aimed to optimize the process of obtaining dried extracts of Peperomia pellucida L. (HBK) by spray drying. The characterization of…
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Design and characterisation of an amorphous formulation of nifedipine for the treatment of autonomic…
Current treatment for autonomic dysreflexia (AD) involves rupturing a liquid-filled soft capsule of nifedipine to aid rapid drug release and absorption, however, this application is not covered under the manufacturer's license. The objective of the current work was to design a rapidly dissolving…
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Impact of co-processed excipient particles solidity and circularity on critical quality attributes…
The selection of appropriate functional co-processed excipient (CPE) is a crucial stage in orodispersible minitablets (ODMTs) development. This paper aimed to identify the most important morphological attributes influencing the flowability and homogeneity of powder mixtures and minitablets final…
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Performance Evaluation of a Novel Biosourced Co-Processed Excipient in Direct Compression and Drug…
This study exposes the potential usefulness of a new co-processed excipient, composed of alginic acid and microcrystalline cellulose (Cop AA-MCC), for the preparation of immediate drug release tablets by direct compression. Evaluation of the physical and mechanical properties as well as the…
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Thermoplastic Cellulose-Based Compound for Additive Manufacturing
The increasing environmental awareness is driving towards novel sustainable high-performance materials applicable for future manufacturing technologies like additive manufacturing (AM). Cellulose is abundantly available renewable and sustainable raw material. This work focused on studying the…
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Rettenmeier Iberica Site in Barcelona, Spain receives EXCiPACT GDP Certification as a Pharmaceutical…
Brussels, 23 March 2021
EXCiPACT asbl is pleased to announce that the Rettenmeier Iberica SL y Cia S.C site in Barcelona, Spain has recently been awarded an EXCiPACT GDP Certificate from Aenor, one of EXCIPACT’s internationally recognised Certification Bodies.
The Certificate demonstrates that…
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Formulation of Medicated Chewing Gum Containing Sceletium tortuosum and Process Optimization…
Sceletium tortuosum is one of the most promising medicinal plant species for treating anxiety and depression. Traditionally, aerial parts are chewed (masticatory herbal medicine) providing fast relief and rendering the masticatory route for delivery, ideal.
This study intended formulating novel…
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Impact of Critical Material Attributes (CMAs)-Particle Shape on Miniature Pharmaceutical Unit…
The U.S. Food and Drug Administration (FDA) emphasizes drug product development by Quality by Design (QbD). Critical material attributes (CMAs) are a QbD element that has an impact on pharmaceutical operations and product quality. Pharmaceutical drugs often crystallize as needle-shaped (a CMA)…
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Evaluating mechanical properties and tabletability of pharmaceutical powders with a novel…
Developing new pharmaceuticals is costly and time-consuming. New methods are always in demand for various stages of product development. Investing in the early phases of development can save a significant amount of resources in the long term.
Tablet is still the most commonly used pharmaceutical…
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3DP Printing of Oral Solid Formulations: A Systematic Review
Three-dimensional (3D) printing is a recent technology, which gives the possibility to manufacture personalised dosage forms and it has a broad range of applications. One of the most developed, it is the manufacture of oral solid dosage and the four 3DP techniques which have been more used for their…
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