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Kerry
The effect of glidant on the tabletting behavior of common pharmaceutical excipients
Abstract
Glidant used for the purpose of powder flowability enhancement is well known within the pharmaceutical industry to improve tablet manufacturing. Despite the widespread use of glidant for this purpose, the effect of glidant on the effect of tableting behavior is not well studied. To address…
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Microencapsulation of hop bioactive compounds by spray drying: Role of inlet temperature and wall…
This study explores the effect of spray-drying (SD) inlet temperatures (Tinlet 120 and 150 °C) and wall material on the chemical and physico-chemical properties of microencapsulated hop extracts (MHE). Hop extract was formulated with maltodextrin (MD) and gum Arabic (GA) used in single or in…
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Vitafoods Geneva 2024 – with a focus on excipients
This year Vitafoods Europe opens its doors for the last time in Geneva at Palexpo.
From 14th to 16th May you can have a face-to-face chat with visitors and exhibitors again.
Pharma Excipients gives you an overview of the excipient suppliers, their booths, main topics and products in the…
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Pharma Acetates – by Kerry
Focused on quality for better health
Pharma acetates are used across a range of pharma applications that require a focus on quality control and product excellence. Using pharma-grade raw materials, our range of Niacet acetates are manufactured to conform with the pharmaceutical industry’s…
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Using AI/ML to predict blending performance and process sensitivity for Continuous Direct…
Utilising three artificial intelligence (AI)/machine learning (ML) tools, this study explores the prediction of fill level in inclined linear blenders at steady state by mapping a wide range of bulk powder characteristics to processing parameters. Predicting fill levels enables the calculation of…
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The influence of directly compressible fillers/diluents on selected compact properties and drug…
Introduction
Direct compression represents a favorable tablet manufacturing method. However, obtaining satisfactory mechanical properties of the compacts and drug dissolution remains a challenge in formulation development, particularly in the case of challenging model drugs. Rivaroxaban is…
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CPHI Barcelona 2023 – with a focus on excipients
This year CPHI Europe opens its doors in Barcelona at Fira Barcelona Gran Via.
From 24th to 26th October you can have a face-to-face chat with visitors and exhibitors again. As usual, InnoPack,
P-MEC, FDF, ICSE and BioProduction will be held together with CPHI.
Pharma Excipients gives you an…
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Lyophilized Lipid Liquid Crystalline Nanoparticles as an Antimicrobial Delivery System
Lipid liquid crystalline nanoparticles (LCNPs) are unique nanocarriers that efficiently deliver antimicrobials through biological barriers. Yet, their wide application as an antimicrobial delivery system is hindered by their poor stability in aqueous dispersions. The production of dried LCNP powder…
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Development of Simvastatin-Loaded Particles Using Spray Drying Method for Ex Tempore Preparation of…
In this work, a spray drying method was developed to produce drug/polymer (simvastatin/polycaprolactone) microparticles that have the potential to be used as a pre-formulation for ex tempore preparation of 2D printing cartridges. An experimental model was designed with the process parameters set to…
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Comparison between polymeric excipients using SeDeM expert system in combination with mathematical…
Based on the quality by design approach, we used the SeDeM expert system to assess seven polymers of different chemical nature and molecular weight for their use in direct compression. Because the SeDeM system fails by not evaluating the mechanical properties of materials, we used the Heckel and…
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