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Kerry
Planetary roller melt granulation (PRMG) – A new continuous method for powder processing
Abstract
For the continuous operation of granulation, which is a standard unit operation in powder processing to modify the particle size, the use of twin-screw machines was established as standard method for wet and melt granulation over the last decade. A main characteristic for this technology…
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A review on co-processed excipients used in direct compression of tablet dosage form
Co-processed excipients may enhance functionality and reduce drawbacks of traditional excipients for the manufacture of tablets on a commercial scale. The following study aimed to characterize a range of co-processed excipients that may prove suitable for dispersible tablet formulations prepared by…
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Enhanced multi-component model to consider the lubricant effect on compressibility and…
Modeling of structural and mechanical tablet properties consisting of multiple components, based on a minimum of experimental data is of high interest, in order to minimize time- and cost-intensive experimental trials in the development of new tablet formulations. The majority of commonly available…
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Surrogate modeling of dissolution behavior toward efficient design of tablet manufacturing processes
This paper presents surrogate models of dissolution behavior to identify the critical input parameters in tablet manufacturing processes. Dissolution behavior is a critical quality attribute, and is defined as the time profile of fraction of dissolved active pharmaceutical ingredients in a solvent…
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Applicability of Expert System for Drug Development as a tool for co-processed excipients…
Expert System for Drug Development, i.e. SeDeM Expert System (Span. Sistema Experto para DEsarrollo de Medicamentos) represents a method intended for evaluation of powder properties affecting processability, particularly compression behavior (Pérez et al., 2006). Additionally, it is recognized as…
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Formulation and Characterisation of Carbamazepine Orodispersible 3D-Printed Mini-Tablets for…
Abstract
One of the main challenges to paediatric drug administration is swallowing difficulties, hindering the acceptability of the medicine and hence clinical outcomes. This study aims at developing a child-appropriate dosage form, the orodispersible mini-tablet (ODMT), using the model drug…
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Formulation-dependent stability mechanisms affecting dissolution performance of directly compressed…
During drug product development, stability studies are used to ensure that the safety and efficacy of a product are not affected during storage. Any change in the dissolution performance of a product must be investigated, as this may indicate a change in the bioavailability. In this study, three…
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Your visit at CPHI worldwide 2022 in Frankfurt
CPHI worldwide opens its doors again. This year in Frankfurt at the Messe Frankfurt. In two weeks, from 1st to 3rd November, you can finally have a face-to-face chat with visitors and exhibitors again. As usual, InnoPack, P-MEC, FDF, ICSE and BioProduction will be held together with CPHI.
The…
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Anhydrous Lactose Family by Kerry
Excipients for direct tabletting and granulation
Product Description
Lactose Overview
Lactose is a disaccharide of glucose and galactose obtained from the whey fraction of bovine milk. Depending on the temperatures used to crystallize and dry the lactose solution, it may be produced in…
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Lactose Spray Dried Monohydrate by Kerry
Excipients for direct tabletting, granulation, capsules, sachet filling and inhalation
Product Description
Lactose Overview
Lactose is a disaccharide of glucose and galactose obtained from the whey fraction of bovine milk. Depending on the temperatures used to crystallize and dry the…
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