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Lubrizol
Spray-dried, Biodegradable, Linezolid loaded Microspheres for Use in the Treatment of Lung Diseases
ABSTRACT
Introduction: Researchers worldwide are currently seeking innovative treatment options to combat the alarming increase in bacterial resistance to antimicrobial drugs. Staphylococcus aureus, a frequently encountered and potentially life-threatening bacterium, has become particularly…
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Systems Biology and Peptide Engineering to Overcome Absorption Barriers for Oral Peptide Delivery:…
Abstract
Oral delivery of peptides and biological molecules promises significant benefits to patients as an alternative to daily injections, but the development of these formulations is challenging due to their low bioavailability and high pharmacokinetic variability. Our earlier work focused on…
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The Preparation and Evaluation of Cyanocobalamin Mucoadhesive Sublingual Tablets
Cobalamin (vitamin B12), an essential vitamin with low oral bioavailability, plays a vital role in cellular functions. This research aimed to enhance the absorption of vitamin B12 using sublingual mucoadhesive tablets by increasing the residence time of the drug at the administration site. This…
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Preparation and formula optimization of cephalexin loaded transferosomal gel by QbD to enhance the…
Most antibiotics used in topical formulations are not absorbed by deeper skin layers and subdermal tissues. Hence the skin infections are treated with large doses of oral or parenteral antibiotics which lead to unpleasant side effects with drug resistance. This could be the necessity for the…
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Formulation And Characterization Of Provesicular Based Drug Delivery System For Effective…
Oral intake of Itraconazole (ITZ) causes severe side effects in the gastrointestinal tract and has low bioavailability ~55%. Owing to these disadvantages, Transdermal drug delivery system (TDDS) of such antifungal agents can overcome such issues and can improve the efficacy and bioavailability. The…
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CPHI Barcelona 2023 – with a focus on excipients
This year CPHI Europe opens its doors in Barcelona at Fira Barcelona Gran Via.
From 24th to 26th October you can have a face-to-face chat with visitors and exhibitors again. As usual, InnoPack,
P-MEC, FDF, ICSE and BioProduction will be held together with CPHI.
Pharma Excipients gives you an…
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Development and Optimization of a Novel Lozenge Containing a Metronidazole-Peppermint Oil-Tranexamic…
In-depth studies on essential oil–based nanoemulsions (NEs) have centered on a variety of oral health issues. NEs improve the delivery of nonpolar active agents to sites and thereby boost the dissolution and distribution of the agents. Metronidazole-peppermint oil-tranexamic acid…
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Tazarotene-calcipotriol loaded Nanostructured lipid carrier enriched hydrogel: A novel dual drug…
Psoriasis with unclear etiology and pathogenesis is one of the most prevalent chronic skin diseases. It involves excessive keratinocytes cells hyperproliferation, abnormal vascular infiltration, and differentiation as its characteristic features. Patients need therapy on a periodic basis over a long…
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Quality by Design-Optimized Glycerosome-Enabled Nanosunscreen Gel of Rutin Hydrate
Sunburn is caused by prolonged exposure to ultraviolet (UV) rays from the sun, resulting in redness of the skin as well as tenderness, swelling, and blistering issues. During the healing process, it can cause peeling, irritation, and some long-term effects, including premature aging, pigmentation,…
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Formulation and in vitro skin diffusion of colchicine using different drug delivery vehicles
Introduction
Historically known as “the disease of kings,” gout is one of the oldest known types of arthritis, affecting more than 40 million people worldwide, prevalent in patients between 30 and 50 years of age, and frequently experienced more by males than females , , , ]. It is a result of…
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