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Merck
Compression Density as an Alternative to Identify an Optimal Moisture Content for High Shear Wet…
Pellet production is a multi-step manufacturing process comprising granulation, extrusion and spheronisation. The first step represents a critical control point, since the quality of the granule mass highly influences subsequent process steps and, consequently, the quality of final pellets. The most…
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Ophthalmics Process by Merck – Keep a close eye on quality and safety
Reduce risk and overcome challenges
Ophthalmic drugs pose special formulation challenges to manufacturers. In general, choosing the right processes and materials is important to ensure the required quality, drug tolerability and patient adherence. Formulators must pay attention to tonicity, pH,…
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Emprove® by Merck: Quality you can count on – Addressing your requirements for parenteral…
Quality, purity, reliability.
Introducing our comprehensive product portfolio.
Sterile liquid applications demand excipients with the highest standards of quality, purity and reliability. To supply everything you need for your medicinal drug product, Merck meets these standards at every stage of…
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Recent advancements in additive manufacturing techniques employed in the pharmaceutical industry: A…
Abstract
The 3–dimensional printing process (3DP) was patented in the 1980s, but the utilization of this process has expanded substantially over the past decade, to which the pharmaceutical industry is a major contributor. With increasing interest, researchers across the globe are striving for the…
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Your visit at CPHI worldwide 2022 in Frankfurt
CPHI worldwide opens its doors again. This year in Frankfurt at the Messe Frankfurt. In two weeks, from 1st to 3rd November, you can finally have a face-to-face chat with visitors and exhibitors again. As usual, InnoPack, P-MEC, FDF, ICSE and BioProduction will be held together with CPHI.
The…
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Development and Evaluation of Dissolving Microarray Patches for Co-administered and Repeated…
Purpose
Whilst significant progress has been made to defeat HIV infection, the efficacy of antiretroviral (ARV) therapy in the paediatric population is often hindered by poor adherence. Currently, two long-acting (LA) intramuscular injectable nanosuspensions of rilpivirine (RPV) and cabotegravir…
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New and Novel Excipients – Part 2
A week ago I wrote about the importance of new and novel excipients for the pharmaceutical industry and presented Klucel™ xtend and BioSustane™ in last week´s edition of "The Excipients Week".
In the meantime I launched a small poll with the title "Was there innovation in excipients over the last…
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Understanding the Multidimensional Effects of Polymorphism, Particle Size and Processing for…
The relevance of the polymorphic form, particle size, and processing of mannitol for the mechanical properties of solid oral dosage forms was examined. Thus, particle and powder properties of spray granulated β D-mannitol, β D-mannitol, and δ D-mannitol were assessed in this study with regards to…
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When coating runs smoothly – Parteck® COAT: Reduce your process time with an optimized polymer…
Our broad range of formulation products covers excipients for solid, semi-solid and liquid dosage forms for small and large molecules. Additionally, we offer a portfolio of drug delivery compounds (DDCs), as well as solutions for solubility enhancement and controlled release. Benefit from our…
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An evaluation of film coating materials and their predicted oro-esophageal gliding performance for…
Oral drug therapy is generally provided in the form of solid oral dosage forms (SODF) that have to be swallowed intact and move throughout the oro-esophageal system until reaching the stomach. Previous studies have provided evidence that the surface characteristics of SODF play an important role…
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