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In this paper, the inclusion complexes (ICs) of hydroxypropyl-beta-cyclodextrin (HPβCD) and risperidone were electrospun into nanofibrous film for potential fast-disintegrating drug delivery system. Risperidone is used to treat bipolar disorder, schizophrenia, and mood swings from autism. However,…
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IFF officially release a new Controlled release platform on 15th of May 2024. Here you get a deeper insight in the  "Timing is Everything" platform where you can learn about pharmaceutical formulations to benefit patients and the importance of controlled release of active ingredients. No…
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THE NEW STYL’ONE NANO is a revolutionary benchtop R&D press for demanding formulation and scientists with price performance in mind. Instruments for every formulation scientist with price performance in mind POWDER COMPACTION SCIENCE CONCENTRATED IN A BENCHTOP R&D PRESS Tableting has…
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L-HPC (low-substituted hydroxypropyl cellulose NF, JP, EP) was developed by Shin-Etsu and first approved in 1977 as a disintegrant for tablets in Japan. New grades were developed during the last years in order to cover the needs for our customer having best solutions for individual applications.…
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People worldwide need to improve their health or intention to control diseases more naturally through ingredients incorporated into foods and beverages, called functional foods. Functional foods include probiotic organisms and bioactive compounds incorporated into dairy and fermentable foods, whose…
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Abstract In the nasal cavity, nasal mucosa had a high blood perfusion rate, due to this the absorption of the drug is high as compared to other routes, as well as has increased good bioavailability of drugs at the systemic circulation. To improve the nasal retention time of in-situ gel with nasal…
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This case study was presented at the 14th World Meeting on Pharmaceutics, Biopharmaceutics and Pharmaceutical Technology, 18 - 21 March 2024, Vienna, Austria: INTRODUCTION The growing interest in probiotic supplements is driven by the favorable effects on intestinal microbiota and contributions to…
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The aim of this research was to develop a process analytical technology (PAT) tool for monitoring the transformation process of the active ingredient ibuprofen into the fast-dissolving salt ibuprofen sodium during the wet granulation process. Two near-infrared (NIR) spectrophotometers, namely…
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Abstract Breast cancer continues to pose a substantial global health challenge, emphasizing the critical need for the advancement of novel therapeutic approaches. Key players in the regulation of apoptosis, a fundamental process in cell death, are the B-cell lymphoma 2 (Bcl-2) family proteins,…
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Production of amorphous solid dispersions (ASDs) is an invaluable technique to promote the solubility and bioavailability of medicinal substances. ASD is manufactured using a variety of classic and modern techniques, most of which rely on either melting or solvent evaporation. This proof-of-concept…
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