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BASF Biopharma Ingredients Portfolio – High Quality Raw Materials for Biopharmaceutical…
Biopharmaceutical manufacturing processes require high-quality raw materials delivered through a transparent and reliable supply chain, supported by experts. BASF Biopharma Ingredients is committed to meeting your requirements for every ingredient we supply to the biologics industry.
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Batch vs. continuous direct compression – a comparison of material processability and final tablet…
Abstract
In this study, an in-depth comparison was made between batch and continuous direct compression using similar compression set-ups. The overall material processability and final tablet quality were compared and evaluated. Correlations between material properties, process parameters and…
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Phospholipid Complex Formulation Technology for Improved Drug Delivery in Oncological Settings: a…
Addressing poor solubility and permeability issues associated with synthetic drugs and naturally occurring active compounds is crucial for improving bioavailability. This review explores the potential of phospholipid complex formulation technology to overcome these challenges. Phospholipids, as…
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Ceolus MCC- Low levels of colored particles
Suppliers of pharmaceuticals and excipients face challenges in controlling technically unavoidable particles (TUPs) to prevent defects and protect brand reputation. Ceolus™, Asahi Kasei´s microcrystalline cellulose (MCC) products demonstrate exceptionally low levels of TUPs thanks to their…
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Expert interview with Marc Müller (Head of Business Development BIOGRUND GmbH) about CompactCel®…
What were the reasons for developing a new disintegrant premix based on natural ingredients?
For years, we have seen an increased interest in a healthy lifestyle on the consumer side. Not only in the USA, but also in Europe, consumers increasingly want to avoid chemical or synthetic ingredients and…
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Enzyme-Linked Lipid Nanocarriers for Coping Pseudomonal Pulmonary Infection
Would Nanocarriers Complement Biofilm Disruption or Pave Its Road?
Introduction: Cystic fibrosis (CF) is associated with pulmonary Pseudomonas aeruginosa infections persistent to antibiotics.
Methods: To eradicate pseudomonal biofilms, solid lipid nanoparticles (SLNs) loaded with…
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Formulation Development, Characterization, and Evaluation of Bedaquiline Fumarate -Soluplus® -Solid…
Bedaquiline fumarate (BQF) is classified as a BCS class II drug and has poor water solubility and dissolution rate, which ultimately compromises bioavailability. The objective of this study is to improve the biopharmaceutical properties of BQF through a solid dispersion system by using Soluplus®.…
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STYL’One Evo R&D – Scale-Up and Production Support
STYL’ONE EVO TABLETING INSTRUMENT
The all-in-one multi-functional R&D press from early API characterization and formulation to scale-up at production speed
The most advanced R&D press designed as multifunction tool adapted to every demanding need from early research to production support…
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Mitigating Particle Formation During Ultrafiltration/Diafiltration of Biologics with KLEPTOSE® HPβCD…
INTRODUCTION
Ultrafiltration/diafiltration (UF/DF) is an integral part of every biotherapeutic downstream process. A typical UF/DF process requires several passes through the pump and the membrane cassette, often taking several hours for completion. During this time, proteins are exposed to several…
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Effect of drug load on the aerosolisation propensity of binary adhesive mixtures for inhalation
Abstract
The aim of this study was to investigate how the propensity for aerosolisation in binary adhesive mixtures was affected by the drug load, and to determine whether these findings could be linked to different blend states. Binary blends of two different lactose carriers, each with varying…
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