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Roquette
INFLUENCE OF BINDER ATTRIBUTES ON BINDER EFFECTIVENESS IN A CONTINUOUS TWIN SCREW WET GRANULATION…
As a switch to continuous twin screw granulation is quickly gaining momentum, the suitability of binders needs to be evaluated towards this novel granulation process. Binder suitability depends on binder effectiveness, which is affected by binder attributes. These critical attributes need to be…
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Roller compaction
Roller compaction is the main technique employed in dry granulation.
Ribbon sticking and splitting are among the major factors that can hinder the use of this process for some formulations. Ribbon splitting can occur either transversally (through the ribbon thickness) or longitudinally (through the…
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Formulation and evaluation of new oxycodone extended release multiple unit pellet system
The goal of the present study is to prepare a stable, multiple-unit, extended-release dosage form containing oxycodone pellets coated with aqueous ethylcellulose (EC) dispersion, Surelease E-7-19050. The application of 18% w/w of EC leads to the similar drug release with the hydrophobic,…
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Solidifying ticagrelor loaded self-microemulsifying drug delivery system
The aim of this study was to solidify a ticagrelor loaded self-microemulsifying drug delivery system (TCG-SM) with enhanced dissolution and bioavailability of ticagrelor (TCG) for developing TCG-SM granules and tablets.
TCG was dissolved in the self-microemulsifying drug delivery system (SMEDDS)…
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Fexofenadine hydrochloride orally disintegrating tablets for pediatric use
17. October 2017
Allergic rhinitis is a common disease in children which has considerable negative effects on the quality of life. Fexofenadine hydrochloride (FFH) is a second-generation oral antihistamine which has been widely perscribed for alleviating symptoms of AR in children.…
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Roquette Announces Commitment to Provide New Product Offerings
21. March 2017
New product offerings are low endotoxin, multi-compendial-grade materials for cell culture and biologic drug formulations. These products extend Roquette's commitment to helping customers save and sustain patients’ lives.
"As a long-time leader in…
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Parenteral preparations, challenges in formulations
The article describes the main challenges encountered during the formulation of parenteral preparations, as well as Roquette’s solutions meeting the formulator’s needs.
Author: Dr Elham Blouet, Global market manager Injectable and Dialysis, Global Business Unit Pharma & Health,…
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Robust Tableting Excipient: Starch-Lactose Compound
17. June 2016
A robust excipient, STARLAC® could be considered as perfect filler binder for direct compression applications, combining fast tablet disintegration with easy tableting.
The co-processed starch-lactose compound STARLAC® is an excipient perfectly adapted to direct…
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Comparative Study Between Different Ready-Made Orally Disintegrating Platforms for the Formulation…
09. April 2016
Sumatriptan succinate (SS) is a selective serotonin receptor agonist used for the treatment of migraine attacks, suffering from extensive first-pass metabolism and low oral bioavailability (∼14%). The aim of this work is to compare the performance of different…
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Lubricants in Pharmaceutical Solid Dosage Forms
Lubrication plays a key role in successful manufacturing of pharmaceutical solid dosage forms; lubricants are essential ingredients in robust formulations to achieve this. Although many failures in pharmaceutical manufacturing operations are caused by issues related to lubrication, in…
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