Pharma Excipients
Suspension Agent
Influence of Sonication on the Molecular Characteristics of Carbopol® and Its Rheological Behavior…
Abstract
The effect of sonication on the molecular characteristics of poliacrylic acid (Carbopol® Ultrez 10) and its rheological behavior in aqueous dispersions and microgels containing 0.25 wt. % of the polymer was analyzed in this work by rheometry, weight-average molecular weight (Mw)…
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Calcipotriol Nanosuspension-Loaded Trilayer Dissolving Microneedle Patches for the Treatment of…
Psoriasis, affecting 2–3% of the global population, is a chronic inflammatory skin condition without a definitive cure. Current treatments focus on managing symptoms. Recognizing the need for innovative drug delivery methods to enhance patient adherence, this study explores a new approach using…
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Novel Patient-Friendly Orodispersible Formulation of Ivermectin is Associated With Enhanced…
Abstract
Ivermectin has been used since the 1980s as an anthelmintic and antiectoparasite agent worldwide. Currently, the only available oral formulation is tablets designed for adult patients. A patient-friendly orodispersible tablet formulation designed for pediatric use (CHILD-IVITAB) has been…
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Methocel™ Cellulose Ethers – A product that can do it all
THE POSSIBILITIES ARE ENDLESS
Pharmaceutical companies are continuously looking for ways to innovate – through new technologies such as controlled release systems and oral films, or through faster and more efficient manufacturing processes. Did you know that just one product can help do all of…
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The science of pharmaceutical suspensions explained! – Explainer video by Pharma Drama
In this video Pharma Drama aka Prof. Simon Gaisford explains how suspensions are formulated and what the medicine is trying to achieve in terms of their properties.
See the video and read the full transcript below.
Read the full video transcript here:
Welcome to Pharma Drama, the…
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Skin-friendly textures – by Gattefossé
Caring for patients
Patient preferences and needs as well as therapeutic indication should be considered at early stage of development of topical or transdermal formulations.
To increase adherence to skin treatments, it is important to consider patient’s needs, when designing the dosage…
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Rheology of amino-functionalized graphene oxide suspensions in hydrogels
This work investigates the effects of amino-functionalized graphene oxide (AFGO) suspensions on the rheological behavior of Carbopol® hydrogels at pHs 5, 7, and 9. The AFGO concentration and media pH were evaluated and related to the suspension's microstructure and rheology. Graphene oxide (GO)…
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Long-Acting Injectable Aqueous Suspensions—Summary From an AAPS Workshop
Through many years of clinical application of long-acting injectables, there is clear proof that this type of formulation does not just provide the patient with convenience, but more importantly a more effective treatment of the medication provided. The formulation approach therefore contains huge…
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Cationic nanocapsule suspension as an alternative to the sublingual delivery of nifedipine
Nifedipine (NIFE) is a calcium channel blocker drug used to treat cardiovascular diseases, angina, and hypertension. However, NIFE is photolabile, has a short biological half-life, low aqueous solubility, and undergoes an intense first-pass effect, compromising its oral bioavailability. Thus, this…
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A Review on Taste Masked Multiparticulate Dosage Forms for Paediatric
Taste refers to those sensations perceived through taste buds on the tongue and oral cavity. The unpleasant taste of drugs leads to the refusal of taking the medicine in the paediatric population. It is widely known that a pharmaceutical product's general acceptability is the result of numerous…
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