Pharma Excipients
Sustained Release Agent
Dissolution improvement of an active pharmaceutical ingredient in a polymer melt by hot melt…
Dissolution of poorly water-soluble active pharmaceutical ingredients (APIs) in polymeric melts plays an important role in the manufacturing of solid dispersions and solid solutions. The understanding of the dissolution is essential for selecting the processing equipment, the operating conditions,…
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Review Oral Modied Release Multiple-Unit Particulate Systems: Compressed Pellets, Microparticles and…
Oral modied-release multiparticulate dosage forms, which are also referred to as oral multiple-unit particulate systems, are becoming increasingly popular for oral drug delivery applications. The compaction of polymer-coated multiparticulates into tablets to produce a sustained-release dosage form…
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Dropwise Additive Manufacturing of Pharmaceutical Products using Particle Suspensions
The principal method of drug delivery is by oral solid doses, the production of which often necessitates multiple post-crystallization unit operations to ensure content uniformity and/or enhance bioavailability. As an alternative to conventional dose production methods, applications of additive…
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3D-Printed Network Structures as Controlled-Release Drug Delivery Systems: Dose Adjustment, API…
07. June 2018
3D printing evolved as a promising technique to improve individualization of drug therapy. In particular, when printing sustained release solid dosage forms, as for instance implants, inserts, andalso tablets, estimation of the drug release profile in vivo …
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