Sweeteners

Broadly speaking, there are three categories of sweeteners – nutritive, sugar alcohols, and high intensity. Sweetener selection is informed by technical, regulatory and clinical considerations as described in the Introduction to Sweeteners. A formulator has many choices in selecting a sweetener, but…
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In this video Chris Moreton gives an interesting insight on pharmaceutical excipients. 
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A compatibility study of drug substance with excipients is a crucial step in the drug development process in order to generate potent final drug formulations for efficient and safe therapy for various diseases. Thus, the development of new methods for compatibility studies is a great challenge. For…
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There are a multitude of sweeteners available to the pharmaceutical scientist. Sweeteners may be broadly grouped into two categories – nutritive and non-nutritive. Nutritive sweeteners deliver calories and as their name suggests, non-nutritive do not. Non-nutritive sweeteners can be…
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Sugars and sweeteners are common ingredients in foods and also in pharmaceutical industries. They are soluble and sticky ingredients and their processing in granulators may be difficult since they can easily adhere to mixer walls or lead to uncontrolled granule growth. The purpose of this…
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Active substances are rarely administered alone. For example, levothyroxine, a synthetic form of the thyroid hormone, indicated in the treatment of hypothyroidism, is administered at a very low dosage, ranging from 15 μg to 200 μg. These very small amounts of powder mean that it is not possible…
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