excipients

See the new book, edited by Shaba Noore , Shivani Pathania , Pablo Fuciños , Colm P. O'Donnell , Brijesh K. Tiwari. Description: This brief provides a comprehensive overview of nanocarriers used for nanoencapsulation of bioactive compounds. It includes the basis of encapsulation mechanism,…
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The WHO has published a new draft guideline on considerations for the prevention and control of nitrosamine contamination in pharmaceutical products. This guideline applies to all manufacturers of excipients, active pharmaceutical ingredients and finished pharmaceutical products. The guideline…
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The field of pharmaceutical 3D printing is growing over the past year, with Spitam® as the first 3D printed dosage form on the market. Showing the suitability of a binder jetting process for dosage forms. Although the development of inks for pharmaceutical field is more trail and error based,…
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1. Introduction The issue of Nitrosamine impurities in drug and excipient manufacturing has become a significant concern for the pharmaceutical industry and health authorities. In June 2018, the FDA was notified of the presence of N-nitrosodimethylamine (NDMA), an impurity found in valsartan, an…
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Tizanidine hydrochloride (TZN) is an antimuscarinic agent used in the treatment of pain-related spasms, multiple sclerosis, and stroke-related spasticity. It has low oral bioavailability (40 %) due to excessive first-pass metabolism in the liver. The aim of this project was to enhance the systemic…
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Abstract The use of a process analytical technology has been demonstrated using near-infrared spectroscopy for continuous manufacturing of pharmaceutical formulations and is within the scope of the U.S. Food and Drug Administration's real-time release testing initiative. While effective for simple…
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In this paper, the inclusion complexes (ICs) of hydroxypropyl-beta-cyclodextrin (HPβCD) and risperidone were electrospun into nanofibrous film for potential fast-disintegrating drug delivery system. Risperidone is used to treat bipolar disorder, schizophrenia, and mood swings from autism. However,…
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IFF officially release a new Controlled release platform on 15th of May 2024. Here you get a deeper insight in the  "Timing is Everything" platform where you can learn about pharmaceutical formulations to benefit patients and the importance of controlled release of active ingredients. No…
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THE NEW STYL’ONE NANO is a revolutionary benchtop R&D press for demanding formulation and scientists with price performance in mind. Instruments for every formulation scientist with price performance in mind POWDER COMPACTION SCIENCE CONCENTRATED IN A BENCHTOP R&D PRESS Tableting has…
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L-HPC (low-substituted hydroxypropyl cellulose NF, JP, EP) was developed by Shin-Etsu and first approved in 1977 as a disintegrant for tablets in Japan. New grades were developed during the last years in order to cover the needs for our customer having best solutions for individual applications.…
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