excipients

Abstract Interest in minitablets (MTs) has grown exponentially over the last 20 years and especially the last decade, as evidenced by the number of publications cited in Scopus and PubMed. MTs offer significant opportunities for personalized medicine, dose titration and flexible dosing, taste…
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Abstract This review provides a comprehensive overview of additive manufacturing (AM) or 3D-printing (3DP) applications in the pharmaceutical industry, with a particular focus on the critical role of polymer selection. By providing insights into how material properties influence the 3DP process and…
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PRESS RELEASE February 27, 2024, Asahi Kasei Corp. Contributing to lower risk of potentially carcinogenic nitrosamine impurities in pharmaceuticals To contribute to reducing the risk of potentially carcinogenic nitrosamine impurities in pharmaceuticals and nutritional supplements, Asahi Kasei…
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Abstract Previous work demonstrated the benefits of dry coating fine-grade microcrystalline cellulose (MCC) for enabling direct compression (DC), a favored tablet manufacturing method, due to enhanced flowability while retaining good compactability of placebo and binary blends of cohesive APIs.…
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Coating is an essential process in the pharmaceutical and nutraceutical industry. Earlier pharmaceutical formulation companies used to buy separate ingredients and mix them for colour coating, but nowadays many manufacturers are involved in making ready premix coating powder and this reduces the…
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Abstract The administration of medications to children has been a challenge for parents and caregivers for generations. Pharmaceutical companies have often overcome the difficulties of weight-based dosing and the ­inability of most young children to swallow solid dosage forms by creating oral…
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Resveratrol (RES) is a biopharmaceutical classification system (BCS) class II compound with low solubility and high permeability. Several strategies have been explored to overcome the low bioavailability of RES, making the formation of solid dispersions (SDs) one of the most promising. This study…
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Polymeric excipients ensure the site-specific delivery of the drug at the desired rate for a specified duration to achieve better efficacy. Pharmaceutical excipients were supposed to be pharmacologically inert, and must assure a controlled rate of delivery, an adjustable pharmacokinetic and…
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The trend toward products with plant-based ingredients continues to grow as a result of customer demand. ADM can help you with high quality, low toxicity ingredients that are cost-effective, bio-compatible and easily available. In addition to providing high-quality APIs and excipients, ADM is…
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Abstract Predicting drug-excipient compatibility is a critical aspect of pharmaceutical formulation design. In this study, we introduced an innovative approach that leverages machine learning techniques to improve the accuracy of drug-excipient compatibility predictions. Mol2vec and 2D molecular…
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