Topical excipients play a crucial role in the formulation of pharmaceutical products intended for external use, such as creams, ointments, gels, and transdermal patches. These excipients serve various purposes, including enhancing drug solubility, ensuring stability, improving drug release, and providing desirable sensory properties.
Pharma Excipients
Topical Excipient
Tocotrienols-Rich Naringenin Nanoemulgel for the Management of Diabetic wound: Fabrication,…
The present research had been attempted to formulate and characterize tocotrienols-rich naringenin nanoemulgel for topical application in chronic wound conditions associated with diabetes. In due course, different phases of the nanoemulsion were chosen based on the solubility study, where…
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A grafted copolymer-based nanomicelles for topical ocular delivery of everolimus: Formulation,…
Treatment of posterior uveitis via topical route is desirable but cannot be achieved by conventional drug delivery strategies. Therefore, the aim of this study is to develop a topical nanomicellar formulation of an immunosuppressant drug, everolimus using Soluplus®, a grafted copolymer of polyvinyl…
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IID-Listed Ingredients for Topical Drug Delivery
Topical formulations can effectively deliver therapeutics to a targeted area, with the added benefits of convenient application and reduced risk of systemic side effects. Due to these advantages, it should come as no surprise that this area of drug delivery is becoming a preferred route of…
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See the new features of the digital formulation assistant ZoomLab™ in February 2021
BASF has released a new version of the digital tool, ZoomLab™ in February 2021. The latest update includes a “Developability Classification of Active Ingredient” module and an expanded “Excipient Database” with 44 new topical excipients. ZoomLab™ is a free online tool from BASF that has been…
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Design of Experiments for the Development of Topical Drug Products
The systematic development of pharmaceutical products using quality tools is highly essential for attaining robust performance by minimizing variability. Design of experiment (DoE) is now considered as an indispensable tool in pharmaceutical development to obtain quality products. Among a variety of…
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Investigation of propellant-free aqueous foams as pharmaceutical carrier systems
Due to their light consistency and good spreadability, aqueous foams are considered as convenient and highly accepted drug carrier systems that are of great importance in the field of topical drug delivery. The production of a stable, easy to dose, preferably environmentally harmless foam…
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Development of pH-sensitive vaginal films based on methacrylate copolymers for topical HIV-1…
Interest is growing in “smart” vaginal microbicides as a strategy to protect women from sexual transmission of human immunodeficiency virus (HIV). The concept is based on the development of products featuring low drug release in acidic media such as vaginal fluid but switch to a fast release…
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An Investigation of the Influence of PEG 400 and PEG-6-Caprylic/Capric Glycerides on Dermal Delivery…
Polyethylene glycols (PEGs) and PEG derivatives are used in a range of cosmetic and pharmaceutical products. However, few studies have investigated the influence of PEGs and their related derivatives on skin permeation, especially when combined with other solvents. Previously, we reported…
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Topical Delivery of Cannabinoids
Providing texture and stability
A short video to explain how Gattefossé all-in-one emulsifiers help simplify topical formulations and enable to obtain a wide range of sensorial textures
Tefose® 63: widely used oil-in-water emulsifier
Gelot™ 64: oil-in-water emulsifier, preferred for high…
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Design of propolis-loaded film forming systems for topical administration: The effect of acrylic…
In situ film forming systems are an alternative to the conventional dosage forms for topical application, performing superior contact and adhesiveness, with a consequent sustained and efficacious therapy. Propolis (PRP) is an extremely versatile natural compound due to its constitutive complexity…
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