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Transdermal
Solid-in-oil nanodispersion as a novel topical transdermal delivery to enhance stability and skin…
l-ascorbic acid (Vitamin C, VC)is the most abundant antioxidant in human skin. But its poor penetration into the skin and unstability limit the application. The aim of the study was to promote the topical skin permeation and retention of VC, increase the stability as well as effectiveness by a novel…
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Hydrogel-forming microarray patch mediated transdermal delivery of tetracycline hydrochloride
Antibiotic resistance is one of the most serious health problems today and is expected to worsen in the coming decades. It has been suggested that antibiotic administration routes that bypass the human gut could potentially tackle this problem. In this work, an antibiotic hydrogel-forming microarray…
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Electrospun nanofibres in drug delivery: advances in controlled release strategies
Emerging drug-delivery systems demand a controlled or programmable or sustained release of drug molecules to improve therapeutic efficacy and patient compliance. Such systems have been heavily investigated as they offer safe, accurate, and quality treatment for numerous diseases. Amongst newly…
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Hydroquinone cream-based polymer microneedle roller for the combined treatment of large-area…
Melasma is a common hyperpigmented skin condition that occurs on the face and other areas prone to light exposure, seriously affecting people's quality of life. Microneedle, a new type of transdermal drug delivery device, can significantly improve skin permeability. In this study, we designed and…
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Dissolvable microneedles for transdermal drug delivery showing skin penetration and modified drug…
Topical therapies for chronic skin diseases suffer from a low patient compliance due to the inconvenient treatment regimens of available products. Dissolvable microneedles (MN) with modified release offer an interesting possibility to increase the compliance by acting as a depot in the skin and…
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Skin drug delivery using lipid vesicles: A starting guideline for their development
Lipid vesicles can provide a cost-effective enhancement of skin drug absorption when vesicle production process is optimised. It is an important challenge to design the ideal vesicle, since their properties and features are related, as changes in one affect the others. Here, we review the main…
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3D-printed EVA-based patches manufactured by direct powder extrusion for personalized transdermal…
In recent years, 3D printing has attracted great interest in the pharmaceutical field as a promising tool for the on-demand manufacturing of patient-centered pharmaceutical forms. Among the existing 3D printing techniques, direct powder extrusion (DPE) resulted as the most practical approach thanks…
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Transdermal delivery of acemetacin loaded microemulsions: preparation, characterization, in vitro –…
The goal of this study was to see if microemulsions might be used as a transdermal drug delivery system for acemetacin (ACM). Microemulsions containing isopropyl myristate, Tween 80, Transcutol HP, Labrafil M1944 CS, ethanol, and distilled water were used to create pseudo-ternary phase diagrams. In…
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Recent approaches for enhancing the performance of dissolving microneedles in drug delivery…
Dissolving microneedles (dMNs) are promising versatile drug delivery systems for the transdermal delivery of numerous drugs, enabling their use in a wide range of biomedical and pharmaceutical applications. Being made of water-soluble polymers, dMNs own several advantages, including fast dissolution…
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Dissolvable microneedles for transdermal drug delivery showing skin pentation and modified drug…
Topical therapies for chronic skin diseases suffer from a low patient compliance due to the inconvenient treatment regimens of available products. Dissolvable microneedles (MN) with modified release offer an interesting possibility to increase the compliance by acting as a depot in the skin and…
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