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Xanthan Gum
Carbohydrates Used in Polymeric Systems for Drug Delivery: From Structures to Applications
Abstract
Carbohydrates, one of the most important compounds in living organisms, perform numerous roles, including those associated with the extracellular matrix, energy-related compounds, and information. Of these, polymeric carbohydrates are a class of substance with a long history in drug…
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Investigation of the effect of polymers on dermal foam properties using the QbD approach
Dermal foams are promising drug delivery systems due to their many advantages and ease of application. Foams are also considered a novelty in the field of dermatology. In particular, they are beneficial for the treatment of skin conditions where patients have highly inflamed, swollen, infected and…
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Bilayer Buccal Tablets of Furosemide: Design and Evaluation
Aim: In the present study, mucoadhesive bilayer buccal tablets of furosemide were fabricated with the objective of avoiding first-pass metabolism and enhancing the bioavailability along with reducing the dosing frequency.
Methodology: Direct compression method was used to prepare bilayer buccal…
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Influence of spray-drying process on properties of chitosan/xanthan gum polyelectrolyte complexes as…
Polyelectrolyte complexes (PECs) are attractive carriers with recognized potential to enhance oral delivery of poorly soluble high-dosed low-molecular-weight drugs. The formulation of solid oral dosage forms requires the drying of PECs, which may affect their physicochemical and biopharmaceutical…
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Optimized hydration dynamics in mucoadhesive xanthan-based trilayer vaginal films for the controlled…
Karaya gum, pectin and xanthan gum have been tested as candidates for manufacturing mucoadhesive trilayer films containing ethylcellulose and chitosan for the vaginal administration of the antiviral Tenofovir (TFV). The swelling profile correlated with the amount of mobile dipoles determined by …
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Development of a Scalable Process of Film-Coated bi-Layer Tablet Containing Sustained-Release…
The development of new drugs that combine active ingredients for the treatment hypertension is critically essential owing to its offering advantages for both patients and manufacturers. In this study, for the first time, detailed development of a scalable process of film-coated bi-layer tablets…
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The interactions in ternary system made of xanthan gum, Carbopol 940 and anionic/nonionic surfactant
The development and optimization of systems consist of polymers and surfactants are strongly related to the presence of interactions between them. Therefore, the interpolymer complexes between biopolymer xanthan gum and synthetic polymer Carbopol 940 were investigated before and after the addition…
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Analysis of Endoscopic Injectability and Post-Ejection Dripping of Yield Stress Fluids: Laponite,…
Yield stress fluids, which show reversible gel–sol transition and a decrease in viscosity via shear, are expected for endoscopic applications. However, quantitative analyses of such fluids, including pressure drop during endoscopic catheter delivery and post-delivery dripping, have not yet been…
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Suspensions and Solutions by IFF Pharma Solutions
Improving patient experience and compliance
Better drug design and delivery options can help improve the likelihood that patients will be more willing to take their medications as prescribed.
Suspensions are defined as finely divided undissolved drugs dispersed in liquid vehicles. They can be a…
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Formulation development and in-vitro evaluation of dexlansoprazole loaded double walled microspheres
In the present work, double walled microspheres of Dexlansoprazole using Sodium alginate, HPMC E15, Xanthan gum, Ethyl cellulose as copolymers and along with Carbopol were formulated to deliver Dexlansoprazole through oral route. Details regarding the preparation and evaluation of the formulations…
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